The postmortem characteristics of Pima Indians of the Gila River Indian Community are investigated so that findings in subjects with and without diabetes mellitus can be correlated with studies in living subjects. Medical records are reviewed for the determination of cause of death and for the occurrence of certain serious diseases or complications of diabetes. The purpose of the study is to relate the outcome and cause of death to events or risk factors measured in life among Pima Indian residents of the Gila River Indian Community, particularly in relation to diabetes, cardiovascular diseases and gallbladder disease. Post-mortem examinations are obtained whenever possible on members of the Gila River Indian Community to ascertain conditions present at the time of death and ascertain cause of death as precisely as possible. In addition, death certificates and all available medical records pertaining to the subjects are obtained and reviewed in a standardized way for evidence of the complications of diabetes, vascular disease, neoplasms and other conditions, which may have been recognized prior to death. The records of the occurrence of such conditions, together with conditions recognized at autopsy, are used to determine the causes of death and incidence of complications associated with diabetes and other conditions identified initially during life by the longitudinal epidemiologic studies in the population.
| Looker, Helen C; Fagot-Campagna, Anne; Gunter, Elaine W et al. (2007) Homocysteine and vitamin B(12) concentrations and mortality rates in type 2 diabetes. Diabetes Metab Res Rev 23:193-201 |
| Hoehner, Christine M; Williams, Desmond E; Sievers, Maurice L et al. (2006) Trends in heart disease death rates in diabetic and nondiabetic Pima Indians. J Diabetes Complications 20:8-13 |
| Jimenez-Corona, Aida; Nelson, Robert G; Sievers, Maurice L et al. (2006) Electrocardiographic abnormalities predict deaths from cardiovascular disease and ischemic heart disease in Pima Indians with type 2 diabetes. Am Heart J 151:1080-6 |
| Pavkov, Meda E; Bennett, Peter H; Sievers, Maurice L et al. (2005) Predominant effect of kidney disease on mortality in Pima Indians with or without type 2 diabetes. Kidney Int 68:1267-74 |
| Saremi, Aramesh; Nelson, Robert G; Tulloch-Reid, Marshall et al. (2005) Periodontal disease and mortality in type 2 diabetes. Diabetes Care 28:27-32 |
| Pavkov, Meda E; Sievers, Maurice L; Knowler, William C et al. (2004) An explanation for the increase in heart disease mortality rates in diabetic Pima Indians: effect of renal replacement therapy. Diabetes Care 27:1132-6 |
| Howard, Barbara V; Rodriguez, Beatriz L; Bennett, Peter H et al. (2002) Prevention Conference VI: Diabetes and Cardiovascular disease: Writing Group I: epidemiology. Circulation 105:e132-7 |
| Jacobsson, L T; Turesson, C; Hanson, R L et al. (2001) Joint swelling as a predictor of death from cardiovascular disease in a population study of Pima Indians. Arthritis Rheum 44:1170-6 |
| Sievers, M L; Bennett, P H; Roumain, J et al. (1999) Effect of hypertension on mortality in Pima Indians. Circulation 100:33-40 |
| Sievers, M L; Bennett, P H; Nelson, R G (1999) Effect of glycemia on mortality in Pima Indians with type 2 diabetes. Diabetes 48:896-902 |
