The purpose of the study is to relate outcome and cause of death to events or risk factors measured in life among Pima Indian residents of the Gila River Indian Community, particularly in relation to diabetes, cardiovascular diseases and gallbladder disease. The causes of death and postmortem characteristics of Pima Indians of the Gila River Indian Community are investigated. Death certificates are obtained on all members of the Gila River Indian Community. Postmortem examination results and all available medical records pertaining to the subjects are obtained to ascertain conditions present at the time of death and ascertain cause of death as precisely as possible. These records are reviewed in a standardized way for evidence of the complications of diabetes, vascular disease, neoplasms and other conditions. The records are used to determine the causes of death and incidence of complications associated with diabetes and other conditions identified initially during life by the longitudinal epidemiologic studies in the population. Detailed review of causes of death from 1965-1994 have been completed. Recent analyses have focussed on the relationships of glycemia and blood pressure to the patterns of underlying causes of death in those with type 2 diabetes mellitus.
| Looker, Helen C; Fagot-Campagna, Anne; Gunter, Elaine W et al. (2007) Homocysteine and vitamin B(12) concentrations and mortality rates in type 2 diabetes. Diabetes Metab Res Rev 23:193-201 |
| Hoehner, Christine M; Williams, Desmond E; Sievers, Maurice L et al. (2006) Trends in heart disease death rates in diabetic and nondiabetic Pima Indians. J Diabetes Complications 20:8-13 |
| Jimenez-Corona, Aida; Nelson, Robert G; Sievers, Maurice L et al. (2006) Electrocardiographic abnormalities predict deaths from cardiovascular disease and ischemic heart disease in Pima Indians with type 2 diabetes. Am Heart J 151:1080-6 |
| Saremi, Aramesh; Nelson, Robert G; Tulloch-Reid, Marshall et al. (2005) Periodontal disease and mortality in type 2 diabetes. Diabetes Care 28:27-32 |
| Pavkov, Meda E; Bennett, Peter H; Sievers, Maurice L et al. (2005) Predominant effect of kidney disease on mortality in Pima Indians with or without type 2 diabetes. Kidney Int 68:1267-74 |
| Pavkov, Meda E; Sievers, Maurice L; Knowler, William C et al. (2004) An explanation for the increase in heart disease mortality rates in diabetic Pima Indians: effect of renal replacement therapy. Diabetes Care 27:1132-6 |
| Howard, Barbara V; Rodriguez, Beatriz L; Bennett, Peter H et al. (2002) Prevention Conference VI: Diabetes and Cardiovascular disease: Writing Group I: epidemiology. Circulation 105:e132-7 |
| Jacobsson, L T; Turesson, C; Hanson, R L et al. (2001) Joint swelling as a predictor of death from cardiovascular disease in a population study of Pima Indians. Arthritis Rheum 44:1170-6 |
| Sievers, M L; Bennett, P H; Roumain, J et al. (1999) Effect of hypertension on mortality in Pima Indians. Circulation 100:33-40 |
| Sievers, M L; Bennett, P H; Nelson, R G (1999) Effect of glycemia on mortality in Pima Indians with type 2 diabetes. Diabetes 48:896-902 |
