Diet and other early exposures may affect child development and the risk of several chronic diseases, but additional research is needed. ? ? The current research described in this catch-all project comprises two project, described below? ? We conducted a study of risk factors for nonalcoholic fatty liver disease among adolescents. This study took advantange of newly available data from the National Health and Nutrition Examination Survey, 1999-2004. The prevalence of this potentially serious condition was found to be suprizingly high--8%.? ? We also conducted a study of determinants of age at menarche among young women in the Collaborative Perinatal Project. The main finding was that, in contrast with a previous study, that exposure to cigarette smoke in utero was unrelated to subsequent age at menarche.? ? Last years progress:? Two papers were published (see list below).
| Eggesbø, Merete; Thomsen, Cathrine; Jørgensen, Jens V et al. (2011) Associations between brominated flame retardants in human milk and thyroid-stimulating hormone (TSH) in neonates. Environ Res 111:737-43 |
| Ye, Xibiao; Qian, Haojun; Xu, Peicheng et al. (2009) Nephrotoxicity, neurotoxicity, and mercury exposure among children with and without dental amalgam fillings. Int J Hyg Environ Health 212:378-86 |
| Fraser, Abigail; Longnecker, Matthew P; Lawlor, Debbie A (2007) Prevalence of elevated alanine aminotransferase among US adolescents and associated factors: NHANES 1999-2004. Gastroenterology 133:1814-20 |
| Gesink Law, D C; Maclehose, R F; Longnecker, M P (2007) Obesity and time to pregnancy. Hum Reprod 22:414-20 |
| Daniels, Julie L; Rowland, Andrew S; Longnecker, Matthew P et al. (2007) Maternal dental history, child's birth outcome and early cognitive development. Paediatr Perinat Epidemiol 21:448-57 |
| Zhou, Haibo; Chen, Jianwei; Rissanen, Tiina H et al. (2007) Outcome-dependent sampling: an efficient sampling and inference procedure for studies with a continuous outcome. Epidemiology 18:461-8 |
| Zhang, Yawei; Graubard, Barry I; Longnecker, Matthew P et al. (2007) Maternal hormone levels and perinatal characteristics: implications for testicular cancer. Ann Epidemiol 17:85-92 |
| Chen, Aimin; Pennell, Michael L; Klebanoff, Mark A et al. (2006) Maternal smoking during pregnancy in relation to child overweight: follow-up to age 8 years. Int J Epidemiol 35:121-30 |
| McGlynn, Katherine A; Graubard, Barry I; Klebanoff, Mark A et al. (2006) Risk factors for cryptorchism among populations at differing risks of testicular cancer. Int J Epidemiol 35:787-95 |
| McGlynn, Katherine A; Graubard, Barry I; Nam, Jun-Mo et al. (2005) Maternal hormone levels and risk of cryptorchism among populations at high and low risk of testicular germ cell tumors. Cancer Epidemiol Biomarkers Prev 14:1732-7 |
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