Abstract

High molecular weight B-cell growth factor augmentation substance continues to elude all efforts at isolation and characterization. Using linked-scan and FAB mass spectrometry, a series of oligosaccharides of interest in demyelinating diseases have been sequenced. The heat stable factor necessary for the steroid binding complex of the adrenocortical pregnenolone binding protein has been identified as adenosine 3',5'- diphosphate. A wide variety of peptides have been analyzed by linked- scan and FAB mass spectrometry

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Intramural Research (Z01)
Project #
1Z01HL001003-20
Application #
3843277
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
20
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
National Heart, Lung, and Blood Institute
Department
Type
DUNS #
City
State
Country
United States
Zip Code

  Publications

Lindh, Rebecka; Ahmad, Faiyaz; Resjo, Svante et al. (2007) Multisite phosphorylation of adipocyte and hepatocyte phosphodiesterase 3B. Biochim Biophys Acta 1773:584-92
Ludwig, Joseph A; Szakacs, Gergely; Martin, Scott E et al. (2006) Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer. Cancer Res 66:4808-15
Goren, Mayer B; Sokoloski, Edward A; Fales, Henry M (2005) 2-Methyl-(1Z,3E)-butadiene-1,3,4-tricarboxylic acid, ""isoprenetricarboxylic acid"". J Org Chem 70:7429-31
Boja, Emily S; Hoodbhoy, Tanya; Garfield, Mark et al. (2005) Structural conservation of mouse and rat zona pellucida glycoproteins. Probing the native rat zona pellucida proteome by mass spectrometry. Biochemistry 44:16445-60
Zhao, Hongtao; Joseph, Joy; Fales, Henry M et al. (2005) Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence. Proc Natl Acad Sci U S A 102:5727-32
Che, Magnus M; Boja, Emily S; Yoon, Hye-Young et al. (2005) Regulation of ASAP1 by phospholipids is dependent on the interface between the PH and Arf GAP domains. Cell Signal 17:1276-88
Davis, David A; Singer, Kathleen E; De La Luz Sierra, Maria et al. (2005) Identification of carboxypeptidase N as an enzyme responsible for C-terminal cleavage of stromal cell-derived factor-1alpha in the circulation. Blood 105:4561-8
Sun, G; Ma, Y; Gao, X et al. (2004) Method for isolating tight-binding inhibitors of rat lens aldose reductase. Exp Eye Res 79:919-26
De La Luz Sierra, Maria; Yang, Fuquan; Narazaki, Masashi et al. (2004) Differential processing of stromal-derived factor-1alpha and stromal-derived factor-1beta explains functional diversity. Blood 103:2452-9
Jeong, Woojin; Chang, Tong-Shin; Boja, Emily S et al. (2004) Roles of TRP14, a thioredoxin-related protein in tumor necrosis factor-alpha signaling pathways. J Biol Chem 279:3151-9

Showing the most recent 10 out of 29 publications