In corpus striatum, Na+-dependent 3H-cocaine binding can be used as a biochemical marker for dopamine uptake sites located in presynaptic dopaminergic terminals. A GABA-modulin-like polypeptide purified from striatal synaptosomes reduces Na+-dependent 3H-cocaine binding to striatal membrane preparations.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Intramural Research (Z01)
Project #
1Z01HL003513-06
Application #
4694624
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
6
Fiscal Year
1985
Total Cost
Indirect Cost
Name
U.S. National Heart Lung and Blood Inst
Department
Type
DUNS #
City
State
Country
United States
Zip Code