Signal averaged electrocardiographic (SAE) detection of late potentials (LP) is a non-invasive method for detection of patients with aubythmogenic ventricle. The purpose of this study was to determine the correlation between SAE and inducibility of sustained ventricular tachycardia invasively by programmed stimulation (PS) in 30 patients with hypertrophic cardiomyopathy. The results show that based on certain LP indices SAE had a sensitivity and specificity of 85% and 94% respectively for induced VT. We conclude that SAE is a useful non-invasive test which in addition to PS may help to identify HCM patients with electrically unstable ventricles who may be at risk of sudden cardiac death.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Intramural Research (Z01)
Project #
1Z01HL004194-02
Application #
3920188
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost
Name
U.S. National Heart Lung and Blood Inst
Department
Type
DUNS #
City
State
Country
United States
Zip Code