A method was developed, utilizing polarized light microscopy and a specially designed microtensile stage, for the simultaneous evaluation of changes in collagen crimp and in biomechanical properties of biomaterials utilized in the fabrication of prosthetic heart valves. This method obviates the need for separate independent measurement of these parameters under various experimental conditions and should be of practical usefulness in the evaluation of new designs of prosthetic heart valves.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Intramural Research (Z01)
Project #
1Z01HL005284-94
Application #
3757744
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
94
Fiscal Year
1994
Total Cost
Indirect Cost
Name
National Heart, Lung, and Blood Institute
Department
Type
DUNS #
City
State
Country
United States
Zip Code