Tetrahydrobiopterin biosynthesis is regulated by the activity of the enzyme, GTP cyclohydrolase. Some endogenous polypeptide inhibitors of GTP cyclohdrolase have been isolated from rat liver which may play a role in its regulation.
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| Mitra, Poulami; Maceyka, Michael; Payne, Shawn G et al. (2007) Ceramide kinase regulates growth and survival of A549 human lung adenocarcinoma cells. FEBS Lett 581:735-40 |
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