Positron Emission Tomography (PET) using 18F)-2-deoxyglucose (FDG) allows us to obtain anatomical data (e.g., axial transverse or coronal images of the brain) as well as dynamic functional data (such as regional cerebral glucose consumption rate, and measurement of storage, degradation and turnover of tagged metabolites). Besides FDG, other radiopharmaceuticals (tagged with 18F, 15O, 11C,13N) can be used with PET to study the BBB, oxygen metabolism, protein synthesis, and neuroreceptors. The unique property of PET is that it provides physiologic and pathophysiologic information not available with any other imaging procedure.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Intramural Research (Z01)
Project #
1Z01NS002315-11
Application #
3945226
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
11
Fiscal Year
1987
Total Cost
Indirect Cost
City
State
Country
United States
Zip Code