Clinical Support Services for the NIAMS Intramural Research Program

Kastner, Daniel

Abstract

This project has provided research infrastructure support for the following clinical protocols: 91-AR-0196 Studies on the Natural History and Pathogenesis of Polymyositis, Dermatomyositis, and Related Diseases 94-AR-0066 Studies of the Pathogenesis and Natural History of Systemic Lupus Erythematosus (SLE) 94-AR-0105 Genetics and Pathophysiology of Familial Mediterranean Fever and Related Disorders 99-D-0070 Natural History of Salivary Gland Dysfunction and Sjogren's Syndrome 00-AR-0222 Studies of the Pathogenesis and Natural History of Arthritis and Related Conditions 01-AR-0227 Natural History of Rheumatic Disease in Minority Communities 02-AR-0156 A Randomized, Double-Blind, Placebo-Controlled Trial of Infliximab in Patients with Dermatomyositis and Polymyositis 03-AR-0130 Genetic Determinants of Ankylosing Spondylitis Severity - Cross Sectional Study 03-AR-0131 Genetic Determinants of Ankylosing Spondylitis Severity - Longitudinal Study 03-AR-0133 Clinically Important Changes in Rheumatoid Arthritis 03-AR-0173 Studies of the Natural History and Pathogenesis of Neonatal Onset Multisystem Inflammatory Disease (NOMID) 03-AR-0298 A Pilot Study of the IL-1 Receptor Antagonist Anakinra/Kineret in Patients with Neonatal Onset Multisystem Inflammatory Disease (NOMID/CINCA Syndrome) 04-AR-0205 Progression of Spinal Fusion in Ankylosing Spondylitis 05-AR-0014 A Pilot Open-Label Study of IL-1 Trap in Adult Subjects with Autoinflammatory Disease: A Therapeutic Approach to Study Pathogenesis 07-E-0012 Rituximab in the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Polymyositis (PM) 08-AR-0008 Insulin Resistance and Atherosclerosis in a Sample of Women with Systemic Lupus Erythematosus 08-AR-0218 Rilonacept to Treat Familial Mediterranean Fever 09-AR-0066 Canakinumab to Treat Neonatal Onset Multisystem Inflammatory Disease

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
• Type: Clinical Support Services Intramural Research (ZID)
• Project #: 1ZIDAR041180-03
• Application #: 8175436
• Support Year: 3
• Fiscal Year: 2010
• Total Cost: $6,138,792

Institution

• Name: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Publications

Katz, James David (2018) At the intersection of self and not-self: finding the locus of 'self' in autoimmunity. Med Humanit 44:137-139

Arthur, Victoria L; Shuldiner, Emily; Remmers, Elaine F et al. (2018) IL1RN Variation Influences Both Disease Susceptibility and Response to Recombinant Human Interleukin-1 Receptor Antagonist Therapy in Systemic Juvenile Idiopathic Arthritis. Arthritis Rheumatol 70:1319-1330

Ferrada, Marcela A; Grayson, Peter C; Banerjee, Shubhasree et al. (2018) Patient Perception of Disease-Related Symptoms and Complications in Relapsing Polychondritis. Arthritis Care Res (Hoboken) 70:1124-1131

Pinal-Fernandez, Iago; Casal-Dominguez, Maria; Mammen, Andrew L (2018) Statins: pros and cons. Med Clin (Barc) 150:398-402

Ward, Michael M; Guthrie, Lori C; Alba, Maria I et al. (2018) Origins of Discordant Responses among 3 Rheumatoid Arthritis Improvement Criteria. J Rheumatol 45:745-752

Grayson, Peter C; Eddy, Sean; Taroni, Jaclyn N et al. (2018) Metabolic pathways and immunometabolism in rare kidney diseases. Ann Rheum Dis 77:1226-1233

Irizarry-Caro, Jorge A; Carmona-Rivera, Carmelo; Schwartz, Daniella M et al. (2018) Brief Report: Drugs Implicated in Systemic Autoimmunity Modulate Neutrophil Extracellular Trap Formation. Arthritis Rheumatol 70:468-474

Gupta, Sarthak; Chan, Diana W; Zaal, Kristien J et al. (2018) A High-Throughput Real-Time Imaging Technique To Quantify NETosis and Distinguish Mechanisms of Cell Death in Human Neutrophils. J Immunol 200:869-879

Weiss, Pamela F; Colbert, Robert A (2018) Juvenile Spondyloarthritis: A Distinct Form of Juvenile Arthritis. Pediatr Clin North Am 65:675-690

Parikh, Prachi; Tavee, Jinny; Soltanzadeh, Payam et al. (2018) Anti-3-hydroxy-3-methylglutaryl-coenzyme a reductase autoantibody-positive necrotizing autoimmune myopathy with dermatomyositis-like eruption. Muscle Nerve 57:E135-E136