Studies will be undertaken to understand two cell behaviors important to tissue engineering: secretion and migration. Understanding these behaviors is important for efficient tissue development in order to replace defective hormones and administer pharmacologic agents. Research will target mechanisms of stimulus-secretion coupling, with emphasis on the role of cell membrane electrophysiology in these mechanisms. Engineering principals are to be applied in the experiments, and mathematical models will be used to investigate cell migration in three-dimensional biological matrices.

Project Start
Project End
Budget Start
1991-11-01
Budget End
1996-10-31
Support Year
Fiscal Year
1991
Total Cost
$280,000
Indirect Cost
Name
University of Houston
Department
Type
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77204