This grant in the Organic and Macromolecular Chemistry Program supports Professor David R. Williams' broad research to explore new synthetic methodology, with advantageous development of advances in acyclic stereocontrol. A specific goal is to allow introduction of nitrogen as a surrogate amine. Overall, these strategies will focus on selective ring forming processes with efficient assembly of stereochemically complex amino-alcohols. The project will investigate the fundamental chemistry of medium-sized cyclic amines and amides as well as the character of 1-aza?5.3.0!bicyclodecanes.
