This project is in the general area of analytical and surface chemistry and in the subfield of liquid chromatography. The thrust of this experimental program focusses on broad, systematic studies of anionic, cationic, and zwitterionic micellar mobile phases in reverse phase liquid chromatography (RPLC), and of reversed (inverted) micellar mobile phases in normal phase liquid chromatography (NPLC). This activity is the first comprehensive study of RPLC selectivity using micelle mobile phases and the NPLC studies are particularly note worthy in that they could lead to the wider use of NPLC through control of water content in the system and to the reliable use of amperometric detection with this powerful chromatographic method. In addition to contributing to an enhanced understanding of fundamental chromatographic science, this research could lead to new and versatile analytical techniques of immense importance to biotechnology research and manufacturing.

Agency
National Science Foundation (NSF)
Institute
Division of Chemistry (CHE)
Type
Standard Grant (Standard)
Application #
8915067
Program Officer
Project Start
Project End
Budget Start
1989-07-01
Budget End
1990-06-30
Support Year
Fiscal Year
1989
Total Cost
$55,000
Indirect Cost
Name
University of Cincinnati
Department
Type
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221