This award from the Chemistry Research Instrumentation and Facilities (CRIF) Program and the Major Research Instrumentation (MRI) Program will assist the Department of Chemistry at Colorado School of Mines acquire a Matrix-Assisted Laser Desorption Ionization/Time of Flight (MALDI/TOF) Mass Spectrometer. This equipment will enhance research in a number of areas, including (a) coupling field-flow fractionation w/MALDI for analysis of bacteria & synthetic polymers; (b) fragmentation and ionization modes in the MALDI of bacterial proteins; (c) molecular weight and chemical species determination in unique polymer systems; and (d) characterization of microbial communities by MALDI of amplified & digested 16S rDNA.
Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules.