This will try to identify homologous regions of the polydnaviruses from different parasitic wasp groups in an attempt to determine the phylogenetic affinities of the viruses. These trees can then be compared to those of the wasps for congruence testing. The polydnavirus association with the wasps is an extremely interesting relationship and represents the only known example of mutualism between eukaryotes and viruses. It appears that the virus is necessary for the wasp to successfully complete its lifecycle since the products that it produces successfully suppresses the host immune response to the parasitoids. A determination of when this trait arose and if it is lineage specific would be highly valuable to a wide range of individuals in the scientific community and may also have wide ranging effects in the insect control community. The procedures to be attempted are new and offer a high potential return if the project is successful.

Agency
National Science Foundation (NSF)
Institute
Division of Environmental Biology (DEB)
Type
Standard Grant (Standard)
Application #
9111938
Program Officer
Scott L. Collins
Project Start
Project End
Budget Start
1991-06-15
Budget End
1992-11-30
Support Year
Fiscal Year
1991
Total Cost
$39,823
Indirect Cost
Name
University of Missouri-Saint Louis
Department
Type
DUNS #
City
Saint Louis
State
MO
Country
United States
Zip Code
63121