HLAVIN 9513877 This conference, organised as a satellite to the annual meeting of the Society for Neuroscience, addresses a topic of rapidly growing importance in the understanding of brain development. Adhesion molecules comprise a diverse set of substances that regulate the development of the brain , and other tissues, by means of intercellular signals which regulate the growth and formation of appropriate connections. L1 is one such molecule. When it is present in a mutant form, abnormal development results. the conference will enable established and younger investigators form related disciplines to share new insights on the significance and mode of action of L1.