Adenovirus is a mammalian virus that contains at least 10 different proteins in an architecture that is complex but creates the virion's characteristically simple icosahedral shape. Adenovirus is an important model in molecular biology with a growing body of knowledge describing its biological properties. Dr. Burnett's aim is to understand the whole virion, at atomic resolution if possible, using crystallography to obtain finely detailed accurate images of those constituent molecules that are crystallizable, electron microscopy to establish the overall relationship among molecules and biochemistry to determine the composition of the virion and its component substructures.

Agency
National Science Foundation (NSF)
Institute
Division of Molecular and Cellular Biosciences (MCB)
Type
GAA (GAA)
Application #
8721431
Program Officer
Arthur Kowalsky
Project Start
Project End
Budget Start
1988-02-15
Budget End
1988-12-01
Support Year
Fiscal Year
1987
Total Cost
$59,700
Indirect Cost
Name
Columbia University
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10027