The main aims are to investigate the interaction of alcohol and the purified BZ/GABA receptor complex protein; to examine the structure- effect relationship between the physiochemical properties of alcohols and their potencies in potentiating the activity of the purified receptor complex protein; and then to realize the molecular mechanism of the action of alcohols on purified receptor level.
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| Yan, G M; Irwin, R P; Lin, S Z et al. (1995) Diphenylhydantoin induces apoptotic cell death of cultured rat cerebellar granule neurons. J Pharmacol Exp Ther 274:983-90 |
| Yan, G M; Ni, B; Weller, M et al. (1994) Depolarization or glutamate receptor activation blocks apoptotic cell death of cultured cerebellar granule neurons. Brain Res 656:43-51 |
