Abstract

Research project exploring surface molecules of alveolar macrophages in response to specific cytokines has been designed to contribute to the problem of molecular mechanisms of cell-cell interactions involved in the immune and inflammatory processes in the lung. Research experience of U.S. sponsors from University of Nebraska Medical Center in the field of bronchoalveolar cell biology promises continuing my study of alveolar macrophages using modern immunological and molecular biological techniques.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Fellowships (FIC) (F05)
Project #
5F05TW004895-02
Application #
2292990
Study Section
International and Cooperative Projects 1 Study Section (ICP)
Project Start
1994-09-01
Project End
Budget Start
1994-09-01
Budget End
1995-08-31
Support Year
2
Fiscal Year
1994
Total Cost
Indirect Cost

  Institution

Name
University of Nebraska Medical Center
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Omaha
State
NE
Country
United States
Zip Code
68198

  Publications

Striz, I; Slavcev, A; Kalanin, J et al. (2001) Cell-cell contacts with epithelial cells modulate the phenotype of human macrophages. Inflammation 25:241-6
Striz, I; Mio, T; Adachi, Y et al. (2000) Effects of interferons alpha and gamma on cytokine production and phenotypic pattern of human bronchial epithelial cells. Int J Immunopharmacol 22:573-85
Striz, I; Mio, T; Adachi, Y et al. (1999) IL-4 induces ICAM-1 expression in human bronchial epithelial cells and potentiates TNF-alpha. Am J Physiol 277:L58-64
Kraft, M; Striz, I; Georges, G et al. (1998) Expression of epithelial markers in nocturnal asthma. J Allergy Clin Immunol 102:376-81
Striz, I; Mio, T; Adachi, Y et al. (1998) The CD14 molecule participates in regulation of IL-8 and IL-6 release by bronchial epithelial cells. Immunol Lett 62:177-81