The use of legal and illegal psychoactive substances is an issue of major concern in our society. Although nicotine dependence, as well as concomitant use of nicotine and other drugs, is highly prevalent, particularly in treatment seeking substance abusers, the potential interactions of nicotine and other substances are not understood. This study is designed to examine the potential interactive effects of acute nicotine administration and chronic alcohol and/or stimulant abuse on brain electrophysiology in detoxified/abstinent substance abusers and community controls. Disentangling the interactive effects of these substances will lead to a better understanding of addictive processes and behavioral outcomes.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Predoctoral Individual National Research Service Award (F31)
Project #
1F31DA006086-01A1
Application #
6405224
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Babecki, Beth
Project Start
2001-08-15
Project End
Budget Start
2001-08-15
Budget End
2002-08-14
Support Year
1
Fiscal Year
2001
Total Cost
$22,623
Indirect Cost
Name
University of Oklahoma Health Sciences Center
Department
Psychiatry
Type
Schools of Medicine
DUNS #
937727907
City
Oklahoma City
State
OK
Country
United States
Zip Code
73117
Ceballos, Natalie A (2006) Tobacco use, alcohol dependence, and cognitive performance. J Gen Psychol 133:375-88
Ceballos, Natalie A; Tivis, Rick; Lawton-Craddock, Andrea et al. (2006) Nicotine and cognitive efficiency in alcoholics and illicit stimulant abusers: implications of smoking cessation for substance users in treatment. Subst Use Misuse 41:265-81
Ceballos, Natalie A; Tivis, Rick; Lawton-Craddock, Andrea et al. (2005) Visual-spatial attention in alcoholics and illicit stimulant abusers: effects of nicotine replacement. Prog Neuropsychopharmacol Biol Psychiatry 29:97-107
Ceballos, Natalie A; Nixon, Sara Jo; Phillips, Julia A et al. (2003) Semantic processing in alcoholics with and without antisocial symptomatology. J Stud Alcohol 64:286-91
Ceballos, Natalie A; Nixon, Sara Jo; Tivis, Rick (2003) Substance abuse-related P300 differences in response to an implicit memory task. Prog Neuropsychopharmacol Biol Psychiatry 27:157-64