Abstract

? The overarching aim of the present NRSA proposal is to delineate empirical linkages between the cognitive risk factor for panic disorder (PD), termed anxiety sensitivity (AS; fear of anxiety), and acute nicotine withdrawal symptoms in order to better understand the etiology of panic vulnerability processes. This proposal links theory and research on cognitive vulnerability for PD with smoking research on acute nicotine withdrawal to test the hypothesis that hypersensitivity to interoceptive cues (i.e., AS) moderates the role of nicotine withdrawal in relation to panic-relevant responding to a carbon dioxide-enriched air (CO2) challenge among daily smokers.
The specific aims of the present study are thus to test whether AS will moderate the relation between pre-challenge nicotine withdrawal and responding to a CO2 procedure (controlling for negative affectivity, anticipatory anxiety, cigarettes per day, and gender), as indexed by: (1) level of anxiety focused on bodily sensations and intensity of panic attack symptoms; (2) level of expired pCO2 and skin conductance reactivity; and (3) greater levels of behavioral avoidance of a future challenge. ? ? ? ? ?

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Predoctoral Individual National Research Service Award (F31)
Project #
1F31DA021006-01
Application #
7058034
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Lawrence, Diane M
Project Start
2006-03-01
Project End
2008-02-29
Budget Start
2006-03-01
Budget End
2007-02-28
Support Year
1
Fiscal Year
2006
Total Cost
$41,652
Indirect Cost

  Institution

Name
University of Vermont & St Agric College
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
066811191
City
Burlington
State
VT
Country
United States
Zip Code
05405

  Publications

Harte, Christopher B; Vujanovic, Anka A; Potter, Carrie M (2015) Association between exercise and posttraumatic stress symptoms among trauma-exposed adults. Eval Health Prof 38:42-52
Vujanovic, Anka A; Farris, Samantha G; Harte, Christopher B et al. (2013) Smoking Status and Exercise in relation to PTSD Symptoms: A Test among Trauma-Exposed Adults. Ment Health Phys Act 6:
Potter, Carrie M; Vujanovic, Anka A; Marshall-Berenz, Erin C et al. (2011) Posttraumatic stress and marijuana use coping motives: the mediating role of distress tolerance. J Anxiety Disord 25:437-43
Vujanovic, Anka A; Bonn-Miller, Marcel O; Marlatt, G Alan (2011) Posttraumatic stress and alcohol use coping motives among a trauma-exposed community sample: the mediating role of non-judgmental acceptance. Addict Behav 36:707-12
Bonn-Miller, Marcel O; Vujanovic, Anka A; Boden, Matthew Tyler et al. (2011) Posttraumatic stress, difficulties in emotion regulation, and coping-oriented marijuana use. Cogn Behav Ther 40:34-44
Vujanovic, Anka A; Marshall, Erin C; Gibson, Laura E et al. (2010) Cognitive-affective characteristics of smokers with and without posttraumatic stress disorder and panic psychopathology. Addict Behav 35:419-25
Rellini, Alessandra H; Vujanovic, Anka A; Zvolensky, Michael J (2010) Emotional dysregulation: concurrent relation to sexual problems among trauma-exposed adult cigarette smokers. J Sex Marital Ther 36:137-53
Vujanovic, Anka A; Marshall-Berenz, Erin C; Beckham, Jean C et al. (2010) Posttraumatic stress symptoms and cigarette deprivation in the prediction of anxious responding among trauma-exposed smokers: a laboratory test. Nicotine Tob Res 12:1080-8
Leyro, Teresa M; Zvolensky, Michael J; Vujanovic, Anka A et al. (2010) Perceived physical health and heart-focused anxiety among daily adult cigarette smokers: associations with affect-relevant smoking motives and outcome expectancies. Cogn Behav Ther 39:11-23
Zvolensky, Michael J; Stewart, Sherry H; Vujanovic, Anka A et al. (2009) Anxiety sensitivity and anxiety and depressive symptoms in the prediction of early smoking lapse and relapse during smoking cessation treatment. Nicotine Tob Res 11:323-31

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