Inhibitors for Coagulation Proteases

Brown, Audra D.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Predoctoral Individual National Research Service Award (F31)
• Project #: 1F31HL008813-01
• Application #: 2213626
• Study Section: Special Emphasis Panel (SRC)
• Project Start: 1993-03-29
• Budget Start: 1992-10-01
• Budget End: 1993-09-30
• Support Year: 1
• Fiscal Year: 1992

Institution

• Name: Georgia Institute of Technology
• Department: Chemistry
• Type: Schools of Arts and Sciences
• DUNS #: 097394084
• City: Atlanta
• State: GA
• Country: United States
• Zip Code: 30332

Publications

Jackson, D S; Brown, A D; Schaeper, R J et al. (1995) A kinetic study of the hydrolysis of the N-tosylalanine ester of 3-hydroxy-5-phenylpyrrole and related compounds by human leukocyte elastase. Arch Biochem Biophys 323:108-14

Brown, A D; Powers, J C (1995) Rates of thrombin acylation and deacylation upon reaction with low molecular weight acylating agents, carbamylating agents and carbonylating agents. Bioorg Med Chem 3:1091-7

Boduszek, B; Brown, A D; Powers, J C (1994) alpha-Aminoalkylphosphonate di(chlorophenyl) esters as inhibitors of serine proteases. J Enzyme Inhib 8:147-58