Positive symptoms, such as delusions and thought disorder, are some of the most puzzling aspects of schizophrenia. However, not all patients are alike in severity and content of these symptoms, and the proposed research will use that variability to understand semantic disturbances in schizophrenia. The project will examine patients' use of semantic information and their memory performance in relation to their symptom profiles. Participants will be presented with a series of word lists, each constructed around a particular semantic theme, and then given a recognition task in which they will respond to words by indicating whether they have been presented earlier. Differences in the use of semantic information will be assessed during this recognition task by examining accuracy and reaction time in addition to ERP component latency and amplitude emphasizing N400 and P300 components.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Predoctoral Individual National Research Service Award (F31)
Project #
5F31MH068123-02
Application #
6792611
Study Section
Special Emphasis Panel (ZRG1-BBBP-5 (01))
Program Officer
Chavez, Mark
Project Start
2003-07-21
Project End
2006-07-20
Budget Start
2004-07-21
Budget End
2005-07-20
Support Year
2
Fiscal Year
2004
Total Cost
$40,154
Indirect Cost
Name
University of Illinois Urbana-Champaign
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
041544081
City
Champaign
State
IL
Country
United States
Zip Code
61820
Fisher, Joscelyn E; Heller, Wendy; Miller, Gregory A (2013) Neuropsychological differentiation of adaptive creativity and schizotypal cognition. Pers Individ Dif 54:70-75
Fisher, Joscelyn E; Sass, Sarah M; Heller, Wendy et al. (2010) Time course of processing emotional stimuli as a function of perceived emotional intelligence, anxiety, and depression. Emotion 10:486-97
Mohanty, Aprajita; Heller, Wendy; Koven, Nancy S et al. (2008) Specificity of emotion-related effects on attentional processing in schizotypy. Schizophr Res 103:129-37
Fisher, Joscelyn E; Heller, Wendy; Miller, Gregory A (2007) Semantic associations, lateralized frontal function, and context maintenance in schizotypy. Neuropsychologia 45:663-72