Current thinking suggests that two cochlear sources contribute to distortion product otoacoustic emissions (DPOAEs), a distortion source and a reflection source. In contrast, low-level stimulus frequency OAEs (SFOAEs) are believed to be dominated by reflection-source contributions. It has been proposed that DPOAEs would more accurately predict behavioral threshold and identify auditory status if the reflection-source contribution is reduced or eliminated, although this hypothesis has not been tested. The broad objective of the proposed study is to determine the influence of cochlear-source contribution on OAE test performance.
Four specific aims are posed. 1) The most effective suppressor tone for reducing the reflection-source contribution to DPOAEs will be determined. 2) Accuracy in predicting behavioral thresholds from traditional (two-source) DPOAEs, distortion-source DPOAEs (reflection source suppressed), and SFOAEs, will be evaluated in normal and impaired human ears. 3) Clinical decision theory will be used to evaluate the accuracy with which dichotomous decisions regarding auditory status are made with two-source (traditional DPOAEs) and single-source OAEs (distortion-source DPOAEs and SFOAEs). 4) The role of fine structure (thought to arise from the complex summation of distortion- and reflection-source energy for DPOAEs) in prediction and diagnostic errors will be evaluated.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
5F32DC007536-02
Application #
7029686
Study Section
Communication Disorders Review Committee (CDRC)
Program Officer
Sklare, Dan
Project Start
2005-03-01
Project End
2006-07-31
Budget Start
2006-03-01
Budget End
2006-07-31
Support Year
2
Fiscal Year
2006
Total Cost
$20,191
Indirect Cost
Name
Father Flanagan's Boys' Home
Department
Type
DUNS #
073136806
City
Boys Town
State
NE
Country
United States
Zip Code
68010
Johnson, Tiffany A; Neely, Stephen T; Kopun, Judy G et al. (2010) Clinical test performance of distortion-product otoacoustic emissions using new stimulus conditions. Ear Hear 31:74-83
Neely, Stephen T; Johnson, Tiffany A; Kopun, Judy et al. (2009) Distortion-product otoacoustic emission input/output characteristics in normal-hearing and hearing-impaired human ears. J Acoust Soc Am 126:728-38
Johnson, Tiffany A; Neely, Stephen T; Kopun, Judy G et al. (2007) Distortion product otoacoustic emissions: cochlear-source contributions and clinical test performance. J Acoust Soc Am 122:3539-53
Johnson, Tiffany A; Neely, Stephen T; Kopun, Judy G et al. (2006) Reducing reflected contributions to ear-canal distortion product otoacoustic emissions in humans. J Acoust Soc Am 119:3896-907
Johnson, Tiffany A; Neely, Stephen T; Garner, Cassie A et al. (2006) Influence of primary-level and primary-frequency ratios on human distortion product otoacoustic emissions. J Acoust Soc Am 119:418-28