Project Start
1990-09-01
Project End
Budget Start
1990-03-01
Budget End
1991-02-28
Support Year
1
Fiscal Year
1990
Total Cost
Indirect Cost
Name
East Carolina University
Department
Type
Schools of Medicine
DUNS #
City
Greenville
State
NC
Country
United States
Zip Code
27858
Friedman, J E; Caro, J F; Pories, W J et al. (1994) Glucose metabolism in incubated human muscle: effect of obesity and non-insulin-dependent diabetes mellitus. Metabolism 43:1047-54
Friedman, J E (1994) Role of glucocorticoids in activation of hepatic PEPCK gene transcription during exercise. Am J Physiol 266:E560-6
Sherman, W M; Friedman, J E; Gao, J P et al. (1993) Glycemia and exercise training alter glucose transport and GLUT4 in the Zucker rat. Med Sci Sports Exerc 25:341-8
Friedman, J E; Yun, J S; Patel, Y M et al. (1993) Glucocorticoids regulate the induction of phosphoenolpyruvate carboxykinase (GTP) gene transcription during diabetes. J Biol Chem 268:12952-7
Friedman, J E; Dohm, G L; Leggett-Frazier, N et al. (1992) Restoration of insulin responsiveness in skeletal muscle of morbidly obese patients after weight loss. Effect on muscle glucose transport and glucose transporter GLUT4. J Clin Invest 89:701-5
Friedman, J E; Dudek, R W; Whitehead, D S et al. (1991) Immunolocalization of glucose transporter GLUT4 within human skeletal muscle. Diabetes 40:150-4
Friedman, J E; de Vente, J E; Peterson, R G et al. (1991) Altered expression of muscle glucose transporter GLUT-4 in diabetic fatty Zucker rats (ZDF/Drt-fa). Am J Physiol 261:E782-8
Houmard, J A; Egan, P C; Neufer, P D et al. (1991) Elevated skeletal muscle glucose transporter levels in exercise-trained middle-aged men. Am J Physiol 261:E437-43
Friedman, J E; Dohm, G L; Elton, C W et al. (1991) Muscle insulin resistance in uremic humans: glucose transport, glucose transporters, and insulin receptors. Am J Physiol 261:E87-94
Dohm, G L; Elton, C W; Friedman, J E et al. (1991) Decreased expression of glucose transporter in muscle from insulin-resistant patients. Am J Physiol 260:E459-63

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