Androgen Repression of Alpha-Subunit Gene Expression

Heckert, Leslie L.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Postdoctoral Individual National Research Service Award (F32)
• Project #: 5F32DK008975-03
• Application #: 2135875
• Study Section: Physiological Sciences Study Section (PSF)
• Program Officer: Margolis, Ronald N
• Project Start: 1995-09-15
• Budget Start: 1995-09-15
• Budget End: 1996-09-14
• Support Year: 3
• Fiscal Year: 1995

Institution

• Name: Case Western Reserve University
• Department: Pharmacology
• Type: Schools of Medicine
• DUNS #: 077758407
• City: Cleveland
• State: OH
• Country: United States
• Zip Code: 44106

Publications

Heckert, L L; Wilson, E M; Nilson, J H (1997) Transcriptional repression of the alpha-subunit gene by androgen receptor occurs independently of DNA binding but requires the DNA-binding and ligand-binding domains of the receptor. Mol Endocrinol 11:1497-506

Heckert, L L; Schultz, K; Nilson, J H (1996) The cAMP response elements of the alpha subunit gene bind similar proteins in trophoblasts and gonadotropes but have distinct functional sequence requirements. J Biol Chem 271:31650-6

Heckert, L L; Schultz, K; Nilson, J H (1995) Different composite regulatory elements direct expression of the human alpha subunit gene to pituitary and placenta. J Biol Chem 270:26497-504