Obesity has become a global health concern because it is linked to such conditions as cardiovascular disease, diabetes, respiratory illness, and others. The work described in this proposal will """"""""contribute to our understanding of the mechanisms underlying obesity and insulin resistance by examining how the pro-obesity hormone ghrelin triggers overeating, weight gain, and hyperglycemia.""""""""

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
5F32DK085834-02
Application #
8018448
Study Section
Special Emphasis Panel (ZDK1-GRB-W (O1))
Program Officer
Castle, Arthur
Project Start
2009-09-15
Project End
2012-09-14
Budget Start
2010-09-15
Budget End
2011-09-14
Support Year
2
Fiscal Year
2010
Total Cost
$47,606
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390
Frazao, Renata; Dungan Lemko, Heather M; da Silva, Regina P et al. (2014) Estradiol modulates Kiss1 neuronal response to ghrelin. Am J Physiol Endocrinol Metab 306:E606-14
Dungan Lemko, Heather M; Elias, Carol F (2012) Kiss of the mutant mouse: how genetically altered mice advanced our understanding of kisspeptin's role in reproductive physiology. Endocrinology 153:5119-29