|
Lash, L H; Nelson, R M; Van Dyke, R A et al. (1990) Purification and characterization of human kidney cytosolic cysteine conjugate beta-lyase activity. Drug Metab Dispos 18:50-4
|
|
Lash, L H; Elfarra, A A; Rakiewicz-Nemeth, D et al. (1990) Bioactivation mechanism of cytotoxic homocysteine S-conjugates. Arch Biochem Biophys 276:322-30
|
|
Lash, L H; Anders, M W (1987) Mechanism of S-(1,2-dichlorovinyl)-L-cysteine- and S-(1,2-dichlorovinyl)-L-homocysteine-induced renal mitochondrial toxicity. Mol Pharmacol 32:549-56
|
|
Dekant, W; Lash, L H; Anders, M W (1987) Bioactivation mechanism of the cytotoxic and nephrotoxic S-conjugate S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine. Proc Natl Acad Sci U S A 84:7443-7
|
|
Kauffman, F C (1987) Conjugation-deconjugation reactions in drug metabolism and toxicity. Fed Proc 46:2434-45
|
|
Elfarra, A A; Lash, L H; Anders, M W (1987) Alpha-ketoacids stimulate rat renal cysteine conjugate beta-lyase activity and potentiate the cytotoxicity of S-(1,2-dichlorovinyl)-L-cysteine. Mol Pharmacol 31:208-12
|
|
Banki, K; Elfarra, A A; Lash, L H et al. (1986) Metabolism of S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine to hydrogen sulfide and the role of hydrogen sulfide in S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine-induced mitochondrial toxicity. Biochem Biophys Res Commun 138:707-13
|
|
Lash, L H; Elfarra, A A; Anders, M W (1986) S-(1,2-dichlorovinyl)-L-homocysteine-induced cytotoxicity in isolated rat kidney cells. Arch Biochem Biophys 251:432-9
|
