Within visual cortex individual areas integrate local information through lateral and columnar intra-areal connections. Primary visual cortex and visual association areas are connected through inter-areal feedforward and feedback connections. In order to gain a better understanding of the relative roles of interareal connections in visual information processing, one of the goals of this proposal is to determine the precise anatomical and functional organization of feeforward and feedback connections between primate visual cortical areas V1 and V2, and to investigate the possible existence of multiple systems of feedforward and feedback connections that relate to different V1 and V2 layers and functional compartments. Furthermore, in order to understand the specific contribution of inter- and intra-areal circuits to the classical and non-classical receptive field properties of visual cortex neurons, a second goal of this proposal is to investigate how the spatial dimensions and organization of individual V2 cells' receptive fields are reflected by the spatial organization of inter-areal V1-to V2 feedforward connections and by intra-areal V2 connections. ? ?

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
1F32EY015609-01A1
Application #
6999527
Study Section
Special Emphasis Panel (ZRG1-F02B (20))
Program Officer
Oberdorfer, Michael
Project Start
2005-12-01
Project End
2008-11-30
Budget Start
2005-12-01
Budget End
2006-11-30
Support Year
1
Fiscal Year
2005
Total Cost
$48,296
Indirect Cost
Name
University of Utah
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
009095365
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
Shushruth, S; Mangapathy, Pradeep; Ichida, Jennifer M et al. (2012) Strong recurrent networks compute the orientation tuning of surround modulation in the primate primary visual cortex. J Neurosci 32:308-21
Schwabe, Lars; Ichida, Jennifer M; Shushruth, S et al. (2010) Contrast-dependence of surround suppression in Macaque V1: experimental testing of a recurrent network model. Neuroimage 52:777-92
Federer, Frederick; Ichida, Jennifer M; Jeffs, Janelle et al. (2009) Four projection streams from primate V1 to the cytochrome oxidase stripes of V2. J Neurosci 29:15455-71
Jeffs, Janelle; Ichida, Jennifer M; Federer, Frederick et al. (2009) Anatomical evidence for classical and extra-classical receptive field completion across the discontinuous horizontal meridian representation of primate area V2. Cereb Cortex 19:963-81
Shushruth, S; Ichida, Jennifer M; Levitt, Jonathan B et al. (2009) Comparison of spatial summation properties of neurons in macaque V1 and V2. J Neurophysiol 102:2069-83
Ichida, Jennifer M; Schwabe, Lars; Bressloff, Paul C et al. (2007) Response facilitation from the ""suppressive"" receptive field surround of macaque V1 neurons. J Neurophysiol 98:2168-81
Angelucci, Alessandra; Bressloff, Paul C (2006) Contribution of feedforward, lateral and feedback connections to the classical receptive field center and extra-classical receptive field surround of primate V1 neurons. Prog Brain Res 154:93-120