Retinoic Acid Receptor and Cellular Differentiation

Clifford, John L.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Postdoctoral Individual National Research Service Award (F32)
• Project #: 3F32GM015857-02S1
• Application #: 2467547
• Study Section: Biological Sciences 2 (BIOL)
• Project Start: 1995-10-01
• Budget Start: 1995-10-01
• Budget End: 1996-09-30
• Support Year: 2
• Fiscal Year: 1997

Institution

• Name: Lab de Genetique Moleculaire Des Eucaryo
• City: Strasbourg
• Country: France

Publications

Chiba, H; Clifford, J; Metzger, D et al. (1997) Specific and redundant functions of retinoid X Receptor/Retinoic acid receptor heterodimers in differentiation, proliferation, and apoptosis of F9 embryonal carcinoma cells. J Cell Biol 139:735-47

Chiba, H; Clifford, J; Metzger, D et al. (1997) Distinct retinoid X receptor-retinoic acid receptor heterodimers are differentially involved in the control of expression of retinoid target genes in F9 embryonal carcinoma cells. Mol Cell Biol 17:3013-20

Clifford, J; Chiba, H; Sobieszczuk, D et al. (1996) RXRalpha-null F9 embryonal carcinoma cells are resistant to the differentiation, anti-proliferative and apoptotic effects of retinoids. EMBO J 15:4142-55

Metzger, D; Clifford, J; Chiba, H et al. (1995) Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase. Proc Natl Acad Sci U S A 92:6991-5