Study of the Catalytic Mechanism of T7 Gene 4 Helicase

Crampton, Donald

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Postdoctoral Individual National Research Service Award (F32)
• Project #: 5F32GM066460-02
• Application #: 6640465
• Study Section: Special Emphasis Panel (ZRG1-F04 (20))
• Program Officer: Tompkins, Laurie
• Project Start: 2002-11-25
• Project End: 2004-11-24
• Budget Start: 2003-11-25
• Budget End: 2004-11-24
• Support Year: 2
• Fiscal Year: 2004
• Total Cost: $47,296

Institution

• Name: Harvard University
• Department: Biochemistry
• Type: Schools of Medicine
• DUNS #: 047006379
• City: Boston
• State: MA
• Country: United States
• Zip Code: 02115

Publications

Crampton, Donald J; Mukherjee, Sourav; Richardson, Charles C (2006) DNA-induced switch from independent to sequential dTTP hydrolysis in the bacteriophage T7 DNA helicase. Mol Cell 21:165-74

Crampton, Donald J; Guo, Shenyuan; Johnson, Donald E et al. (2004) The arginine finger of bacteriophage T7 gene 4 helicase: role in energy coupling. Proc Natl Acad Sci U S A 101:4373-8