PROJECTABSTRACT Childadversityisaglobalpublichealthproblem.Exposuretochildhoodadversitysuchasphysical/sexual abuse,domesticviolence,communityviolence,poverty,neglect,andinstitutionalizationiscommon;?estimates rangefrom12%inEuropeto64%inAsia.Childhoodadversityimpactsbothneurologicalandpsychological developmentandisfrequentlyfoundtobeastrongpredictorofadverseoutcomesinadulthood,includingrisk behaviorssuchasinterpersonalviolence,alcoholproblems,andsexualrisk-taking.Contrarytothecumulative riskmodel,thepredominantframeworkusedtoexplainthisrelationship,distinguishingbetweendeprivation andthreat,theDimensionalModelofAdversityandPsychopathologyarguesthatthereareuniqueemotional, cognitive,andneurobiologicalpathwaysthatunderlietheassociationbetweendimensionsofchildadversity anddevelopmentaloutcomes.However,importantly,therehavenotbeenstudiesfromlow-and-middleincome countrycontexts,whereitispossiblethattheenvironmentalandculturalcontextcouldmoderatethe relationshipbetweenadversityandcognitivefunctioning.Theburdenofpsychologicalconditionsfallsheavilyin thesecountries.However,psychologicalresearchfocusesnarrowlyonAmericans,whocompriselessthan5 percentoftheworld?spopulation.
The specificaims ofthisresearchareto:(1)Identifytheelementsof adversityinearlyandmiddlechildhoodandtheirrelatedriskbehavioroutcomesinadolescenceandyoung adulthood;?(2)DeterminetowhatextenttherelationshipsinAim1aremediatedbydifferentindicatorsof cognitivefunctioningandemotionalregulation;?(3)Determinetowhatextenttherelationshipsbetweenthe elementsofadversityinearlyandmiddlechildhoodandtheindicatorsofcognitivefunctioningandemotional regulationaremoderatedbyparentingbehaviorsandculturalnormsofparenting;?and(4)Tounderstandthe effectsoftheresearchcross-culturallyandacrossdifferentlongitudinaldatasets.Thisstudywillutilize longitudinalcohortdatafromParentingAcrossCulturesandYoungLives-Peru.Together,thesesources contain17wavesofdataamong3cohorts,spanningchildhood,adolescence,andyoungadulthoodwith participantsfrom10differentcountries.Thisinvestigationcanhelptoinforminterventionstrategiestoprevent riskybehaviorsamongyouthwhohavebeenexposedtoadverseexperiencesinchildhood.Tosupportthe successfulexecutionofthisresearchprojectandpromotetheapplicant?sgrowthintoanindependent investigator,additionaltrainingduringthefellowshipperiodwillbesoughttoenhancetheapplicant?sresearch network,quantitativeanalysisskills,andsubjectmatterknowledgeindevelopmentalneuroscience.Together, thisproposedresearchandtrainingplanwilllaythefoundationfortheapplicant?sfuturecareerasan independentlyfundeddevelopmentalscienceresearcherfocusedonthecognitiveandemotionaldevelopment ofchildrenandyouthwhohavebeenexposedtoadversity.

Public Health Relevance

With strong evidence for the association between adverse experiences in childhood and risky health behaviors in young adulthood, research is needed to explore the neuropsychological developmental mechanisms of this relationship, particularly among those in low and middle- income countries. This research is aimed at examining whether cognitive factors mediate this relationship and whether it is different for different types of adverse exposures. Findings will fill an important gap in the literature, providing insight into modifiable mechanisms in this pathway, in order to inform intervention strategies to prevent risky behaviors among youth who have been exposed to adverse experiences in childhood.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
1F32HD100159-01
Application #
9834149
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Esposito, Layla E
Project Start
2019-11-01
Project End
2022-10-31
Budget Start
2019-11-01
Budget End
2020-10-31
Support Year
1
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Duke University
Department
Type
Other Specialized Schools
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705