Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
5F32HL008572-02
Application #
2213340
Study Section
Clinical Trials (CLIN)
Project Start
1993-09-01
Project End
Budget Start
1993-09-01
Budget End
1994-03-31
Support Year
2
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Sherman, P M; Lawrence, D A; Verhamme, I M et al. (1995) Identification of tissue-type plasminogen activator-specific plasminogen activator inhibitor-1 mutants. Evidence that second sites of interaction contribute to target specificity. J Biol Chem 270:9301-6
Lawrence, D A; Olson, S T; Palaniappan, S et al. (1994) Engineering plasminogen activator inhibitor 1 mutants with increased functional stability. Biochemistry 33:3643-8
Lawrence, D A; Berkenpas, M B; Palaniappan, S et al. (1994) Localization of vitronectin binding domain in plasminogen activator inhibitor-1. J Biol Chem 269:15223-8
Lawrence, D A; Olson, S T; Palaniappan, S et al. (1994) Serpin reactive center loop mobility is required for inhibitor function but not for enzyme recognition. J Biol Chem 269:27657-62