Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Postdoctoral Individual National Research Service Award (F32)
Project #
5F32HL008635-02
Application #
2213398
Study Section
Clinical Trials (CLIN)
Project Start
1993-07-01
Project End
Budget Start
1993-07-01
Budget End
1994-06-30
Support Year
2
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
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Levine, G N; Frei, B; Koulouris, S N et al. (1996) Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation 93:1107-13
Keaney Jr, J F; Xu, A; Cunningham, D et al. (1995) Dietary probucol preserves endothelial function in cholesterol-fed rabbits by limiting vascular oxidative stress and superoxide generation. J Clin Invest 95:2520-9
Keaney Jr, J F; Vita, J A (1995) Atherosclerosis, oxidative stress, and antioxidant protection in endothelium-derived relaxing factor action. Prog Cardiovasc Dis 38:129-54
Hare, J M; Keaney Jr, J F; Balligand, J L et al. (1995) Role of nitric oxide in parasympathetic modulation of beta-adrenergic myocardial contractility in normal dogs. J Clin Invest 95:360-6
Keaney Jr, J F; Shwaery, G T; Xu, A et al. (1994) 17 beta-estradiol preserves endothelial vasodilator function and limits low-density lipoprotein oxidation in hypercholesterolemic swine. Circulation 89:2251-9
Keaney Jr, J F; Gaziano, J M; Xu, A et al. (1994) Low-dose alpha-tocopherol improves and high-dose alpha-tocopherol worsens endothelial vasodilator function in cholesterol-fed rabbits. J Clin Invest 93:844-51
Keaney Jr, J F; Gaziano, J M; Xu, A et al. (1993) Dietary antioxidants preserve endothelium-dependent vessel relaxation in cholesterol-fed rabbits. Proc Natl Acad Sci U S A 90:11880-4