The objective of this project is to identify the mechanisms contributing to orthostatic intolerance in the heat. This objective will be accomplished by comparing the effects of normothermia versus whole-body heating on hemodynamic factors relating to orthostatic tolerance, on cerebrovascular autoregulation, on presynaptic control of sudomotor and vasomotor function, and adrenoceptor-mediated cutaneous vasoconstriction. This integrated research approach will be able to identify potential mechanisms leading to orthostatic intolerance in the heat.
| Wang, Qilong; Xie, Zhonglin; Zhang, Wencheng et al. (2014) Myeloperoxidase deletion prevents high-fat diet-induced obesity and insulin resistance. Diabetes 63:4172-85 |
| Wilson, Thad E; Crandall, Craig G (2011) Effect of thermal stress on cardiac function. Exerc Sport Sci Rev 39:12-7 |
