The research will provide an examination of four key neurotransmitters (GABA, glutamate, dopamine, and acetylcholine) that are believed to play important roles in alcohol behavioral effects and motivational behaviors. The unique value in the proposed research fellowship is that it will provide state of the art training in neurochemical techniques for the measurement of the extracellular concentrations of each neurotransmitter and to measure two and potentially all concurrently. Measurement will be to determine the effects of injection and self-administration of alcohol. The research will provide new information about the role of these neurotransmitters in alcohol abuse and alcoholism.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
National Research Service Awards for Senior Fellows (F33)
Project #
1F33AA014074-01
Application #
6585378
Study Section
Special Emphasis Panel (ZAA1-GG (26))
Program Officer
Egli, Mark
Project Start
2003-02-01
Project End
Budget Start
2003-02-01
Budget End
2004-01-31
Support Year
1
Fiscal Year
2003
Total Cost
$56,308
Indirect Cost
Name
Princeton University
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
002484665
City
Princeton
State
NJ
Country
United States
Zip Code
08544
Molina, Juan Carlos; Spear, Norman E; Spear, Linda P et al. (2007) The International society for developmental psychobiology 39th annual meeting symposium: Alcohol and development: beyond fetal alcohol syndrome. Dev Psychobiol 49:227-42
Lewis, M J; Rada, P; Johnson, D F et al. (2005) Galanin and alcohol dependence: neurobehavioral research. Neuropeptides 39:317-21
Lewis, Michael J; Johnson, Deanne F; Waldman, Daniel et al. (2004) Galanin microinjection in the third ventricle increases voluntary ethanol intake. Alcohol Clin Exp Res 28:1822-8