Tanjala S. Purnell, PhD MPH is a second-year Assistant Professor in the Department of Surgery at the Johns Hopkins School of Medicine with a joint faculty appointment in the Department of Epidemiology at the Johns Hopkins Bloomberg School of Public Health. She seeks this Mentored Research Scientist Development (K01) Award in patient-centered outcomes research (PCOR) to support her long-term career goal of establishing her independence as a health services researcher and social epidemiologist dedicated to identifying and implementing patient-centered interventions to achieve equity in access to kidney transplantation. During this award, she will pursue a rigorous research and didactic program, including advanced coursework, seminars, and mentored research that will substantially build her skills in developing patient- and stakeholder-engaged interventions to address disparities in access to kidney transplantation for patients with end stage renal disease (ESRD), a condition that results in poor clinical and patient-reported outcomes. Her research and career objectives are closely aligned with the AHRQ's mission of engaging patients and stakeholders in the design and conduct of PCOR to improve clinical and patient-reported outcomes for priority populations. In her research program, Dr. Purnell will characterize the associations of patient and community stressors with disparities in completion of the KT evaluation process (Aim 1). She will also engage patients, family members, health education experts, and clinical providers in the development (Aim 2) and pilot testing (Aim 3) of patient- centered educational materials about the KT evaluation process. These studies were developed based upon direct patient feedback regarding unmet concerns about the KT process and will lay the foundation for future research to test the effectiveness of patient-centered decision support in reducing disparities in access to KT. In her didactic program, she will undergo intensive training in stakeholder-engaged and translational research, qualitative research methods, development of patient-centered interventions, and the design and conduct of randomized clinical trials within the rich training environments of the Johns Hopkins Epidemiology Research Group in Organ Transplantation, Johns Hopkins Center to Eliminate Cardiovascular Health Disparities, Johns Hopkins Center for Health Services and Outcomes Research, and the Welch Center for Prevention, Epidemiology, and Clinical Research. She will receive primary mentorship from Dorry Segev, MD PhD and Lisa A. Cooper, MD MPH and guidance from an exemplary team of faculty advisors and patient stakeholders who are committed to her success and will support the research and didactic goals of this application.

Public Health Relevance

In accordance with the Agency for Healthcare Research and Quality's mission to support patient-centered outcomes research in priority patient populations, this project aims to engage patient stakeholders in the design and conduct of patient-centered outcomes research to address pervasive disparities in access to kidney transplantation for underserved adults with end-stage renal disease.

Agency
National Institute of Health (NIH)
Institute
Agency for Healthcare Research and Quality (AHRQ)
Type
Research Scientist Development Award - Research & Training (K01)
Project #
5K01HS024600-05
Application #
10005324
Study Section
Healthcare Research Training (HCRT)
Program Officer
Willis, Tamara
Project Start
2016-09-30
Project End
2021-09-29
Budget Start
2020-09-30
Budget End
2021-09-29
Support Year
5
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Surgery
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21205
Warsame, Fatima; Haugen, Christine E; Ying, Hao et al. (2018) Limited health literacy and adverse outcomes among kidney transplant candidates. Am J Transplant :
Henderson, Macey L; Adler, Joel T; Van Pilsum Rasmussen, Sarah E et al. (2018) How Should Social Media Be Used in Transplantation? A Survey of The American Society of Transplant Surgeons. Transplantation :
Mogul, Douglas B; Luo, Xun; Chow, Eric K et al. (2018) Impact of Race and Ethnicity on Outcomes for Children Waitlisted for Pediatric Liver Transplantation. J Pediatr Gastroenterol Nutr 66:436-441
Henderson, Macey L; DiBrito, Sandra R; Thomas, Alvin G et al. (2018) Landscape of Living Multiorgan Donation in the United States: A Registry-Based Cohort Study. Transplantation 102:1148-1155
Ruck, Jessica M; Holscher, Courtenay M; Purnell, Tanjala S et al. (2018) Factors associated with perceived donation-related financial burden among living kidney donors. Am J Transplant 18:715-719
Eno, Ann K; Thomas, Alvin G; Ruck, Jessica M et al. (2018) Assessing the Attitudes and Perceptions Regarding the Use of Mobile Health Technologies for Living Kidney Donor Follow-Up: Survey Study. JMIR Mhealth Uhealth 6:e11192
Cooper, Lisa A; Purnell, Tanjala S; Showell, Nakiya N et al. (2018) Progress on Major Public Health Challenges: The Importance of Equity. Public Health Rep 133:15S-19S
Purnell, Tanjala S; Luo, Xun; Cooper, Lisa A et al. (2018) Association of Race and Ethnicity With Live Donor Kidney Transplantation in the United States From 1995 to 2014. JAMA 319:49-61
Henderson, M L; Thomas, A G; Shaffer, A et al. (2017) The National Landscape of Living Kidney Donor Follow-Up in the United States. Am J Transplant 17:3131-3140
Kumar, Komal; Holscher, Courtenay M; Luo, Xun et al. (2017) Persistent regional and racial disparities in nondirected living kidney donation. Clin Transplant 31: