Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Scientist Development Award - Research (K02)
Project #
1K02DA000260-01
Application #
2116312
Study Section
Special Emphasis Panel (SRCD (11))
Project Start
1996-05-01
Project End
2001-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Medical Br Galveston
Department
Pharmacology
Type
Schools of Medicine
DUNS #
041367053
City
Galveston
State
TX
Country
United States
Zip Code
77555
Herin, David V; Bubar, Marcy J; Seitz, Patricia K et al. (2013) Elevated Expression of Serotonin 5-HT(2A) Receptors in the Rat Ventral Tegmental Area Enhances Vulnerability to the Behavioral Effects of Cocaine. Front Psychiatry 4:2
Anastasio, Noelle C; Gilbertson, Scott R; Bubar, Marcy J et al. (2013) Peptide inhibitors disrupt the serotonin 5-HT2C receptor interaction with phosphatase and tensin homolog to allosterically modulate cellular signaling and behavior. J Neurosci 33:1615-30
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Lanfranco, Maria Fe; Anastasio, Noelle C; Seitz, Patricia K et al. (2010) Quantification of RNA editing of the serotonin 2C receptor (5-HT(?C)R) ex vivo. Methods Enzymol 485:311-28
Anastasio, Noelle C; Lanfranco, Maria Fe; Bubar, Marcy J et al. (2010) Serotonin 5-HT2C receptor protein expression is enriched in synaptosomal and post-synaptic compartments of rat cortex. J Neurochem 113:1504-15
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Lanfranco, Maria Fe; Seitz, Patricia K; Morabito, Michael V et al. (2009) An innovative real-time PCR method to measure changes in RNA editing of the serotonin 2C receptor (5-HT(2C)R) in brain. J Neurosci Methods 179:247-57
Nic Dhonnchadha, B A; Fox, R G; Stutz, S J et al. (2009) Blockade of the serotonin 5-HT2A receptor suppresses cue-evoked reinstatement of cocaine-seeking behavior in a rat self-administration model. Behav Neurosci 123:382-96
Leggio, Gian Marco; Cathala, Adeline; Moison, Delphine et al. (2009) Serotonin2C receptors in the medial prefrontal cortex facilitate cocaine-induced dopamine release in the rat nucleus accumbens. Neuropharmacology 56:507-13
Navailles, Sylvia; Moison, Delphine; Cunningham, Kathryn A et al. (2008) Differential regulation of the mesoaccumbens dopamine circuit by serotonin2C receptors in the ventral tegmental area and the nucleus accumbens: an in vivo microdialysis study with cocaine. Neuropsychopharmacology 33:237-46

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