Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Scientist Development Award - Research (K02)
Project #
5K02MH000699-10
Application #
2239938
Study Section
Molecular, Cellular, and Developmental Neurobiology Review Committee (MCDN)
Project Start
1987-08-01
Project End
1997-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Illinois at Chicago
Department
Physiology
Type
Schools of Medicine
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612

  Publications

Rasenick, M M; Chaney, K A; Chen, J (1996) G protein-mediated signal transduction as a target of antidepressant and antibipolar drug action: evidence from model systems. J Clin Psychiatry 57 Suppl 13:49-55;discussion 56-8
Chen, J; Rasenick, M M (1995) Chronic treatment of C6 glioma cells with antidepressant drugs increases functional coupling between a G protein (Gs) and adenylyl cyclase. J Neurochem 64:724-32
Chen, J; Rasenick, M M (1995) Chronic antidepressant treatment facilitates G protein activation of adenylyl cyclase without altering G protein content. J Pharmacol Exp Ther 275:509-17
Rasenick, M M; Watanabe, M; Lazarevic, M B et al. (1994) Synthetic peptides as probes for G protein function. Carboxyl-terminal G alpha s peptides mimic Gs and evoke high affinity agonist binding to beta-adrenergic receptors. J Biol Chem 269:21519-25
Popova, J S; Johnson, G L; Rasenick, M M (1994) Chimeric G alpha s/G alpha i2 proteins define domains on G alpha s that interact with tubulin for beta-adrenergic activation of adenylyl cyclase. J Biol Chem 269:21748-54
Roychowdhury, S; Rasenick, M M (1994) Tubulin-G protein association stabilizes GTP binding and activates GTPase: cytoskeletal participation in neuronal signal transduction. Biochemistry 33:9800-5
Roychowdhury, S; Wang, N; Rasenick, M M (1993) G protein binding and G protein activation by nucleotide transfer involve distinct domains on tubulin: regulation of signal transduction by cytoskeletal elements. Biochemistry 32:4955-61
Lazarevic, M B; Yan, K; Swedler, W I et al. (1992) Effect of gold compounds on the activity of adenylyl cyclase in human lymphocyte membranes. Arthritis Rheum 35:857-64
Wang, N; Rasenick, M M (1991) Tubulin-G protein interactions involve microtubule polymerization domains. Biochemistry 30:10957-65
Ozawa, H; Rasenick, M M (1991) Chronic electroconvulsive treatment augments coupling of the GTP-binding protein Gs to the catalytic moiety of adenylyl cyclase in a manner similar to that seen with chronic antidepressant drugs. J Neurochem 56:330-8

Showing the most recent 10 out of 16 publications