Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Modified Research Career Development Award (K04)
Project #
7K04AI001230-04
Application #
2442355
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1994-07-01
Project End
1999-06-30
Budget Start
1997-01-01
Budget End
1997-06-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Axler-Diperte, Grace L; Miller, Virginia L; Darwin, Andrew J (2006) YtxR, a conserved LysR-like regulator that induces expression of genes encoding a putative ADP-ribosyltransferase toxin homologue in Yersinia enterocolitica. J Bacteriol 188:8033-43
Miller, Virginia L (2002) Connections between transcriptional regulation and type III secretion? Curr Opin Microbiol 5:211-5
Darwin, A J; Miller, V L (2001) The psp locus of Yersinia enterocolitica is required for virulence and for growth in vitro when the Ysc type III secretion system is produced. Mol Microbiol 39:429-44
Schmiel, D H; Young, G M; Miller, V L (2000) The Yersinia enterocolitica phospholipase gene yplA is part of the flagellar regulon. J Bacteriol 182:2314-20
Badger, J L; Young, B M; Darwin, A J et al. (2000) Yersinia enterocolitica ClpB affects levels of invasin and motility. J Bacteriol 182:5563-71
Darwin, K H; Miller, V L (2000) The putative invasion protein chaperone SicA acts together with InvF to activate the expression of Salmonella typhimurium virulence genes. Mol Microbiol 35:949-60
Darwin, K H; Miller, V L (1999) InvF is required for expression of genes encoding proteins secreted by the SPI1 type III secretion apparatus in Salmonella typhimurium. J Bacteriol 181:4949-54
Young, G M; Smith, M J; Minnich, S A et al. (1999) The Yersinia enterocolitica motility master regulatory operon, flhDC, is required for flagellin production, swimming motility, and swarming motility. J Bacteriol 181:2823-33
Darwin, A J; Miller, V L (1999) Identification of Yersinia enterocolitica genes affecting survival in an animal host using signature-tagged transposon mutagenesis. Mol Microbiol 32:51-62
Young, G M; Schmiel, D H; Miller, V L (1999) A new pathway for the secretion of virulence factors by bacteria: the flagellar export apparatus functions as a protein-secretion system. Proc Natl Acad Sci U S A 96:6456-61

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