Abstract

The purpose of this research is to establish the combined effects of applied load and chemical degradation on failure of articulating surfaces of ultra high molecular weight polyethylene total joint replacement components. Three areas will be studied: 1) the cyclic loading conditions which will cause small defects on and below the articulating surface to propagate and create the surface damage modes generated by fatigue fracture mechanisms observed on retrieved components: 2) the extent of chemical degradation occurring to polyethylene joint components as a function of chemical environment and loading history; and 3) the effect of chemical degradation on surface damage modes generated by fatigue fracture mechanisms. These studies will establish a comprehensive understanding of the integrated chemical, mechanical and structural behavior of polyethylene as used in total joint replacements. The goal is to maximize the long-term performance of polyethylene joint components.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Modified Research Career Development Award (K04)
Project #
5K04AR001876-02
Application #
3071418
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Project Start
1992-01-01
Project End
1996-12-31
Budget Start
1993-01-01
Budget End
1993-12-31
Support Year
2
Fiscal Year
1993
Total Cost
Indirect Cost

  Institution

Name
Hospital for Special Surgery
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10021

  Publications

Gadeleta, S J; Boskey, A L; Paschalis, E et al. (2000) A physical, chemical, and mechanical study of lumbar vertebrae from normal, ovariectomized, and nandrolone decanoate-treated cynomolgus monkeys (Macaca fascicularis). Bone 27:541-50
Kurtz, S M; Rimnac, C M; Bartel, D L (1998) Predictive model for tensile true stress-strain behavior of chemically and mechanically degraded ultrahigh molecular weight polyethylene. J Biomed Mater Res 43:241-8
Kurtz, S M; Bartel, D L; Rimnac, C M (1998) Postirradiation aging affects stress and strain in polyethylene components. Clin Orthop Relat Res :209-20
Kurtz, S M; Rimnac, C M; Bartel, D L (1997) Degradation rate of ultra-high molecular weight polyethylene. J Orthop Res 15:57-61
Astion, D J; Saluan, P; Stulberg, B N et al. (1996) The porous-coated anatomic total hip prosthesis: failure of the metal-backed acetabular component. J Bone Joint Surg Am 78:755-66
Kurtz, S M; Rimnac, C M; Santner, T J et al. (1996) Exponential model for the tensile true stress-strain behavior of as-irradiated and oxidatively degraded ultra high molecular weight polyethylene. J Orthop Res 14:755-61
Camacho, N P; Rimnac, C M; Meyer Jr, R A et al. (1995) Effect of abnormal mineralization on the mechanical behavior of X-linked hypophosphatemic mice femora. Bone 17:271-8
Pruitt, L; Koo, J; Rimnac, C M et al. (1995) Cyclic compressive loading results in fatigue cracks in ultra high molecular weight polyethylene. J Orthop Res 13:143-6
Rimnac, C M; Klein, R W; Betts, F et al. (1994) Post-irradiation aging of ultra-high molecular weight polyethylene. J Bone Joint Surg Am 76:1052-6
Huk, O L; Bansal, M; Betts, F et al. (1994) Polyethylene and metal debris generated by non-articulating surfaces of modular acetabular components. J Bone Joint Surg Br 76:568-74

Showing the most recent 10 out of 11 publications