Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Modified Research Career Development Award (K04)
Project #
5K04CA001711-05
Application #
2084338
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1992-08-01
Project End
1997-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
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Hong, Y; Holley-Guthrie, E; Kenney, S (1997) The bZip dimerization domain of the Epstein-Barr virus BZLF1 (Z) protein mediates lymphoid-specific negative regulation. Virology 229:36-48
Zalani, S; Coppage, A; Holley-Guthrie, E et al. (1997) The cellular YY1 transcription factor binds a cis-acting, negatively regulating element in the Epstein-Barr virus BRLF1 promoter. J Virol 71:3268-74
Zhang, Q; Hong, Y; Dorsky, D et al. (1996) Functional and physical interactions between the Epstein-Barr virus (EBV) proteins BZLF1 and BMRF1: Effects on EBV transcription and lytic replication. J Virol 70:5131-42
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Zalani, S; Holley-Guthrie, E; Kenney, S (1996) Epstein-Barr viral latency is disrupted by the immediate-early BRLF1 protein through a cell-specific mechanism. Proc Natl Acad Sci U S A 93:9194-9
Zalani, S; Holley-Guthrie, E; Kenney, S (1995) The Zif268 cellular transcription factor activates expression of the Epstein-Barr virus immediate-early BRLF1 promoter. J Virol 69:3816-23
Gutsch, D E; Holley-Guthrie, E A; Zhang, Q et al. (1994) The bZIP transactivator of Epstein-Barr virus, BZLF1, functionally and physically interacts with the p65 subunit of NF-kappa B. Mol Cell Biol 14:1939-48
Gutsch, D E; Marcu, K B; Kenney, S C (1994) The Epstein-Barr virus BRLF1 gene product transactivates the murine and human c-myc promoters. Cell Mol Biol (Noisy-le-grand) 40:747-60
Zhang, Q; Gutsch, D; Kenney, S (1994) Functional and physical interaction between p53 and BZLF1: implications for Epstein-Barr virus latency. Mol Cell Biol 14:1929-38