Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Modified Research Career Development Award (K04)
Project #
5K04CA064421-03
Application #
2106878
Study Section
Pathology B Study Section (PTHB)
Project Start
1994-09-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Pathology
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Masumoto, Junya; Zhou, Weibin; Chen, Felicia F et al. (2003) Caspy, a zebrafish caspase, activated by ASC oligomerization is required for pharyngeal arch development. J Biol Chem 278:4268-76
Liu, R; Page, C; Beidler, D R et al. (1999) Overexpression of Bcl-x(L) promotes chemotherapy resistance of mammary tumors in a syngeneic mouse model. Am J Pathol 155:1861-7
Koseki, T; Inohara, N; Chen, S et al. (1999) CIPER, a novel NF kappaB-activating protein containing a caspase recruitment domain with homology to Herpesvirus-2 protein E10. J Biol Chem 274:9955-61
Hu, Y; Benedict, M A; Ding, L et al. (1999) Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis. EMBO J 18:3586-95
Ekhterae, D; Lin, Z; Lundberg, M S et al. (1999) ARC inhibits cytochrome c release from mitochondria and protects against hypoxia-induced apoptosis in heart-derived H9c2 cells. Circ Res 85:e70-7
Inohara, N; Koseki, T; Chen, S et al. (1999) Identification of regulatory and catalytic domains in the apoptosis nuclease DFF40/CAD. J Biol Chem 274:270-4
del Peso, L; Gonzalez, V M; Hernandez, R et al. (1999) Regulation of the forkhead transcription factor FKHR, but not the PAX3-FKHR fusion protein, by the serine/threonine kinase Akt. Oncogene 18:7328-33
Wu, D; Chen, P J; Chen, S et al. (1999) C. elegans MAC-1, an essential member of the AAA family of ATPases, can bind CED-4 and prevent cell death. Development 126:2021-31
Inohara, N; Koseki, T; del Peso, L et al. (1999) Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB. J Biol Chem 274:14560-7
Nunez, G; Benedict, M A; Hu, Y et al. (1998) Caspases: the proteases of the apoptotic pathway. Oncogene 17:3237-45

Showing the most recent 10 out of 27 publications