The Candidate, a gastroenterologist/health services researcher has developed a focused research program in cancer prevention and control, primarily through the use of large population-based databases. In addition, he has mentored several trainees and junior faculty at different levels of training. However, because of time and budgetary restraints, his ability to provide data and methodological support to junior researchers is increasingly limited. In addition, he has been unable to expand his research focus to different cancer sites and other content areas, including pharmacoepidemiology. The proposed Established Investigator Award in Cancer Prevention, Control Behavioral and Population Research will assist the Candidate in fulfilling his long-term career goals. These include to evaluate the effectiveness of commonly performed screening, treatment and surveillance procedures in routine clinical practice; determine the accuracy, completeness and appropriateness of alternative methods to measure cancer screening, surveillance, and therapy; and develop a critical mass of cancer prevention and control researchers. The proposal will enable the Candidate to use data sources with which has considerable experience to study other clinically relevant issues. He will investigate the recognition of pre-malignant conditions of the esophagus and its impact on patient outcome, as well as the frequency of use and clinical impact of endoscopic ultrasonography on the diagnosis and treatment of patients with gastrointestinal cancer. In addition, we will develop expertise in the use of pharmacy databases to study the protective effects of non-steroidal anti-inflammatory drugs on colorectal cancer incidence. The resources of this award will also enable aim to develop an infrastructure that will provide the necessary data and research support to train junior investigators in the use of large databases to conduct cancer related health services research.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Scientist Award (K05)
Project #
1K05CA090677-01A1
Application #
6430632
Study Section
Subcommittee G - Education (NCI)
Program Officer
Lohrey, Nancy
Project Start
2002-02-01
Project End
2007-01-31
Budget Start
2002-02-01
Budget End
2003-01-31
Support Year
1
Fiscal Year
2002
Total Cost
$132,408
Indirect Cost
Name
Case Western Reserve University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Cooper, Gregory S; Kou, Tzyung Doug; Chak, Amitabh (2009) Receipt of previous diagnoses and endoscopy and outcome from esophageal adenocarcinoma: a population-based study with temporal trends. Am J Gastroenterol 104:1356-62
Cummings, Linda C; Cooper, Gregory S (2008) Descriptive epidemiology of esophageal carcinoma in the Ohio Cancer Registry. Cancer Detect Prev 32:87-92
Cummings, Linda C; Payes, Jonathan D; Cooper, Gregory S (2007) Survival after hepatic resection in metastatic colorectal cancer: a population-based study. Cancer 109:718-26
Diggs, Jessica C; Xu, Fang; Diaz, Mireya et al. (2007) Failure to screen: predictors and burden of emergency colorectal cancer resection. Am J Manag Care 13:157-64
Koroukian, Siran M; Xu, Fang; Dor, Avi et al. (2006) Colorectal cancer screening in the elderly population: disparities by dual Medicare-Medicaid enrollment status. Health Serv Res 41:2136-54
Cooper, Gregory S; Johnson, Christine Cole; Lamerato, Lois et al. (2006) Use of guideline recommended follow-up care in cancer survivors: routine or diagnostic indications? Med Care 44:590-4
Cooper, Gregory S; Payes, Jonathan D (2006) Temporal trends in colorectal procedure use after colorectal cancer resection. Gastrointest Endosc 64:933-40
El-Serag, Hashem B; Petersen, Laura; Hampel, Howard et al. (2006) The use of screening colonoscopy for patients cared for by the Department of Veterans Affairs. Arch Intern Med 166:2202-8
Das, Ananya; Chak, Amitabh; Cooper, Gregory S (2006) Temporal trend in relative risk of second primary colorectal cancer. Am J Gastroenterol 101:1342-7
Boolchand, Vikram; Olds, Gregory; Singh, Joseph et al. (2006) Colorectal screening after polypectomy: a national survey study of primary care physicians. Ann Intern Med 145:654-9

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