Three studies of health behavior change among persons at high risk of cancer are proposed. The relationship between personal evaluations of the high risk situation and behaviors to avoid incidence or mortality of cancer are examined in each study. The influence of experimental interventions to alter screening and preventive behavior are evaluated. Three populations will be studied. 1) Unaffected twins of cancer cases identified through the International Twin Study will be studied to determine behavior change among persons with close familial cancer incidence. A mass mailed intervention will be tested experimentally to determine the influence on screening or prevention behavior. 2) First degree relatives of bilateral premenopausal breast cancer cases will be studied to determine their screening behavior, their receptivity to participating in a screening program, and the effect on stage of diagnosis of screened, unscreened, and out-of-area subjects. 3) Gay men who have persistent generalized lymphadenopathy (HTLV-III positive) but not diagnosed with AIDS and healthy gay men will be surveyed to identify the extent and determinants of sexual behavior change and drug use behavior change.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Academic/Teacher Award (ATA) (K07)
Project #
5K07CA001203-02
Application #
3076756
Study Section
(SRC)
Project Start
1986-09-01
Project End
1991-08-31
Budget Start
1987-09-01
Budget End
1988-08-31
Support Year
2
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Southern California
Department
Type
Schools of Pharmacy
DUNS #
041544081
City
Los Angeles
State
CA
Country
United States
Zip Code
90033
Richardson, J L; Mondrus, G T; Danley, K et al. (1996) Impact of a mailed intervention on annual mammography and physician breast examinations among women at high risk of breast cancer. Cancer Epidemiol Biomarkers Prev 5:71-6
Richardson, J L; Danley, K; Mondrus, G T et al. (1995) Adherence to screening examinations for colorectal cancer after diagnosis in a first-degree relative. Prev Med 24:166-70
Richardson, J L; Danley, K; Mondrus, G T et al. (1993) Mammography and physician breast exams after the diagnosis of breast cancer in a twin or non-twin sister. Cancer Causes Control 4:251-60
Richardson, J L; Koprowski, C; Mondrus, G T et al. (1993) Perceived change in food frequency among women at elevated risk of breast cancer. Nutr Cancer 20:71-8
Richardson, J L; Langholz, B; Bernstein, L et al. (1992) Stage and delay in breast cancer diagnosis by race, socioeconomic status, age and year. Br J Cancer 65:922-6