The objectives of this transfusion medicine academic program are 1) to broaden the awardee's theoretical, clinical and laboratory expertise in transfusion medicine; 2) to develop an effective curriculum in transfusion medicine for veterinary students, trainees clinicians and faculties; 3) to provide a state-of-the-art blood center for animals; and 40 to increase transfusion medicine-related research by developing and utilizing naturally-occurring animal models for human health and disease. The awardee will be released from other responsibilities allowing him to focus his attention on transfusion medicine. The awardee's expertise and skills will be developed through studying transfusion-related literature, attending transfusion medicine meetings and participating in human blood bank and bone marrow transplant centers. he will continue transfusion medicine-related research, develop and provide expertise on veterinary transfusion research and perform collaborative research with on-campus and other medical centers. An educational committee will be formed by the awardee to develop, coordinate and expand an effective transfusion medicine program for undergraduate and postgraduate students in veterinary medicine. Outstanding veterinary students and postgraduates will be attracted in transfusion medicine teaching and research through offering lectures a special library, an excellent blood bank for animals, and work study/ independent study and research projects. Special seminars will increase the awareness and proficiency in veterinary transfusion medicine. These programs will be developed, evaluated and modified with an educational consultant. With the expertise of the University Hospital's blood bank and transplant center, a high quality animal blood bank will be developed for the small and large animal hospital which will also be used in transfusion medicine-related animal research and pre- and postgraduate training. Research in transfusion medicine will be emphasized in the Veterinary Hospitals, animal models will be developed and characterized by expanding the existing Center for Animal Models of Human Genetic Disease. This Center plans to perform bone marrow transplants and gene replacement therapy with these animal models and expertise in transfusion medicine is essential. The Dean and Department Chairmen of the School of Veterinary Medicine enthusiastically support this TMAA and have give a strong commitment to continue an excellent teaching and research program in transfusion medicine after termination of the award.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Academic/Teacher Award (ATA) (K07)
Project #
1K07HL002355-01
Application #
3077504
Study Section
(SRC)
Project Start
1989-09-01
Project End
1994-08-31
Budget Start
1989-09-01
Budget End
1990-08-31
Support Year
1
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Type
Schools of Veterinary Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Griot-Wenk, M E; Giger, U (1999) The AB blood group system in wild felids. Anim Genet 30:144-7
Skelly, B J; Wallace, M; Rajpurohit, Y R et al. (1999) Identification of a 6 base pair insertion in West Highland White Terriers with erythrocyte pyruvate kinase deficiency. Am J Vet Res 60:1169-72
Kohn, B; Henthorn, P S; Rajpurohit, Y et al. (1999) Feline adult beta-globin polymorphism reflected in restriction fragment length patterns. J Hered 90:177-81
Callan, M B; Shofer, F S; Wojenski, C et al. (1998) Chrono-lume and magnesium potentiate aggregation of canine but not human platelets in citrated platelet-rich plasma. Thromb Haemost 80:176-80
Kohn, B; Reilly, M P; Asakura, T et al. (1998) Polymorphism of feline beta-globins studied by reversed-phase high-performance liquid chromatography. Am J Vet Res 59:830-5
Giger, U; Casal, M L (1997) Feline colostrum--friend or foe: maternal antibodies in queens and kittens. J Reprod Fertil Suppl 51:313-6
Hasler, A H; Giger, U (1996) Serum erythropoietin values in polycythemic cats. J Am Anim Hosp Assoc 32:294-301
Callan, M B; Oakley, D A; Shofer, F S et al. (1996) Canine red blood cell transfusion practice. J Am Anim Hosp Assoc 32:303-11
Casal, M L; Jezyk, P F; Giger, U (1996) Transfer of colostral antibodies from queens to their kittens. Am J Vet Res 57:1653-8
Griot-Wenk, M E; Callan, M B; Casal, M L et al. (1996) Blood type AB in the feline AB blood group system. Am J Vet Res 57:1438-42

Showing the most recent 10 out of 30 publications