Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Academic/Teacher Award (ATA) (K07)
Project #
1K07MH001370-01A1
Application #
2241017
Study Section
Mental Disorders of Aging Review Committee (MDA)
Project Start
1996-08-01
Project End
2001-04-30
Budget Start
1996-08-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Vlassenko, Andrei; Sheline, Yvette I; Fischer, Keith et al. (2004) Cerebral perfusion response to successful treatment of depression with different serotoninergic agents. J Neuropsychiatry Clin Neurosci 16:360-3
Sheline, Yvette I; Gado, Mokhtar H; Kraemer, Helena C (2003) Untreated depression and hippocampal volume loss. Am J Psychiatry 160:1516-8
Sheline, Y I; Mittler, B L; Mintun, M A (2002) The hippocampus and depression. Eur Psychiatry 17 Suppl 3:300-5
Sheline, Yvette I; Mintun, Mark A; Moerlein, Stephen M et al. (2002) Greater loss of 5-HT(2A) receptors in midlife than in late life. Am J Psychiatry 159:430-5
Sheline, Y I; Barch, D M; Donnelly, J M et al. (2001) Increased amygdala response to masked emotional faces in depressed subjects resolves with antidepressant treatment: an fMRI study. Biol Psychiatry 50:651-8
Sheline, Y I (2000) 3D MRI studies of neuroanatomic changes in unipolar major depression: the role of stress and medical comorbidity. Biol Psychiatry 48:791-800
Lenze, E; Cross, D; McKeel, D et al. (1999) White matter hyperintensities and gray matter lesions in physically healthy depressed subjects. Am J Psychiatry 156:1602-7
Sheline, Y I; Sanghavi, M; Mintun, M A et al. (1999) Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression. J Neurosci 19:5034-43
Lenze, E J; Sheline, Y I (1999) Absence of striatal volume differences between depressed subjects with no comorbid medical illness and matched comparison subjects. Am J Psychiatry 156:1989-91
Uzunova, V; Sheline, Y; Davis, J M et al. (1998) Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine. Proc Natl Acad Sci U S A 95:3239-44

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