Abstract

The overall objective of the proposed research program is to study the impact of cataract extraction and intraocular lens implantation on the visual functional status of elderly adults and to refine and validate a simple clinical strategy to distinguish patients who are likely to benefit from cataract extraction and intraocular lens implantation from those who would not. In this context, the applicant proposes a program with these specific aims: 1) to develop and validate a clinical prediction rule based on preoperative measures of functional status and clinical characteristics to predict clinical outcomes one year after surgery; and 2) to refine a vision-specific measure of visual functional status developed by the applicant.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08AG000605-04
Application #
2048411
Study Section
Biological and Clinical Aging Review Committee (BCA)
Project Start
1993-07-01
Project End
1998-06-30
Budget Start
1995-07-01
Budget End
1996-06-30
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
University of California Los Angeles
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095

  Publications

Mangione, C M; Lee, P P; Gutierrez, P R et al. (2001) Development of the 25-item National Eye Institute Visual Function Questionnaire. Arch Ophthalmol 119:1050-8
Mangione, C M; Gutierrez, P R; Lowe, G et al. (1999) Influence of age-related maculopathy on visual functioning and health-related quality of life. Am J Ophthalmol 128:45-53
Lee, B L; Gutierrez, P; Gordon, M et al. (1998) The Glaucoma Symptom Scale. A brief index of glaucoma-specific symptoms. Arch Ophthalmol 116:861-6
Mangione, C M; Berry, S; Spritzer, K et al. (1998) Identifying the content area for the 51-item National Eye Institute Visual Function Questionnaire: results from focus groups with visually impaired persons. Arch Ophthalmol 116:227-33
Mangione, C M; Lee, P P; Pitts, J et al. (1998) Psychometric properties of the National Eye Institute Visual Function Questionnaire (NEI-VFQ). NEI-VFQ Field Test Investigators. Arch Ophthalmol 116:1496-504
DuBeau, C E; Levy, B; Mangione, C M et al. (1998) The impact of urge urinary incontinence on quality of life: importance of patients' perspective and explanatory style. J Am Geriatr Soc 46:683-92
Goldzweig, C L; Mittman, B S; Carter, G M et al. (1997) Variations in cataract extraction rates in Medicare prepaid and fee-for-service settings. JAMA 277:1765-8
Mangione, C M; Goldman, L; Orav, E J et al. (1997) Health-related quality of life after elective surgery: measurement of longitudinal changes. J Gen Intern Med 12:686-97
Mangione, C M; Orav, E J; Lawrence, M G et al. (1995) Prediction of visual function after cataract surgery. A prospectively validated model. Arch Ophthalmol 113:1305-11
Mangione, C M; Phillips, R S; Lawrence, M G et al. (1994) Improved visual function and attenuation of declines in health-related quality of life after cataract extraction. Arch Ophthalmol 112:1419-25