Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08AR001866-04
Application #
2077348
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Project Start
1991-09-01
Project End
1996-08-31
Budget Start
1994-09-01
Budget End
1995-08-31
Support Year
4
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Bloch, D B; Nakajima, A; Gulick, T et al. (2000) Sp110 localizes to the PML-Sp100 nuclear body and may function as a nuclear hormone receptor transcriptional coactivator. Mol Cell Biol 20:6138-46
Bloch, D B; Chiche, J D; Orth, D et al. (1999) Structural and functional heterogeneity of nuclear bodies. Mol Cell Biol 19:4423-30
Chiche, J D; Schlutsmeyer, S M; Bloch, D B et al. (1998) Adenovirus-mediated gene transfer of cGMP-dependent protein kinase increases the sensitivity of cultured vascular smooth muscle cells to the antiproliferative and pro-apoptotic effects of nitric oxide/cGMP. J Biol Chem 273:34263-71
Filippov, G; Bloch, D B; Bloch, K D (1997) Nitric oxide decreases stability of mRNAs encoding soluble guanylate cyclase subunits in rat pulmonary artery smooth muscle cells. J Clin Invest 100:942-8
Bloch, D B; de la Monte, S M; Guigaouri, P et al. (1996) Identification and characterization of a leukocyte-specific component of the nuclear body. J Biol Chem 271:29198-204
Bloch, D B; Rabkina, D; Bloch, K D (1995) The cell proliferation-associated protein Ki-67 is a target of autoantibodies in the serum of MRL mice. Lab Invest 73:366-71
Kawai, N; Bloch, D B; Filippov, G et al. (1995) Constitutive endothelial nitric oxide synthase gene expression is regulated during lung development. Am J Physiol 268:L589-95
Bloch, K D; Wolfram, J R; Brown, D M et al. (1995) Three members of the nitric oxide synthase II gene family (NOS2A, NOS2B, and NOS2C) colocalize to human chromosome 17. Genomics 27:526-30
Bloch, D B; San Martin, J E; Rauch, S D et al. (1995) Serum antibodies to heat shock protein 70 in sensorineural hearing loss. Arch Otolaryngol Head Neck Surg 121:1167-71
Bloch, D B; Rabkina, D; Quertermous, T et al. (1994) The immunoreactive region in a novel autoantigen contains a nuclear localization sequence. Clin Immunol Immunopathol 72:380-9

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