Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Clinical Investigator Award (CIA) (K08)
Project #
5K08CA060498-03
Application #
2101254
Study Section
Cancer Institutional Fellowship Review Committee (CT)
Project Start
1994-09-30
Project End
1999-09-29
Budget Start
1996-09-30
Budget End
1997-09-29
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Yale University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520

  Publications

Dunbar, M E; Wysolmerski, J J (2001) Mammary ductal and alveolar development: lesson learned from genetically manipulated mice. Microsc Res Tech 52:163-70
Foley, J; King, C S; Jimenez, J A et al. (2000) Activation of PTHrP gene expression in squamous carcinoma cell lines by mutant isoforms of the tumor suppressor p53. Oncol Res 12:71-81
Dunbar, M E; Wysolmerski, J J (1999) Parathyroid hormone-related protein: a developmental regulatory molecule necessary for mammary gland development. J Mammary Gland Biol Neoplasia 4:21-34
Dunbar, M E; Dann, P R; Robinson, G W et al. (1999) Parathyroid hormone-related protein signaling is necessary for sexual dimorphism during embryonic mammary development. Development 126:3485-93
Foley, J; Wysolmerski, J J; Missero, C et al. (1999) Regulation of parathyroid hormone-related protein gene expression in murine keratinocytes by E1A isoforms: a role for basal promoter and Ets-1 site. Mol Cell Endocrinol 156:13-23
Dunbar, M E; Young, P; Zhang, J P et al. (1998) Stromal cells are critical targets in the regulation of mammary ductal morphogenesis by parathyroid hormone-related protein. Dev Biol 203:75-89
Wysolmerski, J J; Philbrick, W M; Dunbar, M E et al. (1998) Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland development. Development 125:1285-94
Philbrick, W M; Wysolmerski, J J; Galbraith, S et al. (1996) Defining the roles of parathyroid hormone-related protein in normal physiology. Physiol Rev 76:127-73
Foley, J; Wysolmerski, J J; Broadus, A E et al. (1996) Parathyroid hormone-related protein gene expression in human squamous carcinoma cells is repressed by mutant isoforms of p53. Cancer Res 56:4056-62
Wysolmerski, J J; McCaughern-Carucci, J F; Daifotis, A G et al. (1995) Overexpression of parathyroid hormone-related protein or parathyroid hormone in transgenic mice impairs branching morphogenesis during mammary gland development. Development 121:3539-47